The Bernardes Group

Publications

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  • Currently displaying 161 - 180 of 266 publications
Author(s)
Publication title
Journal Name
Publication year
Site-selective installation of an electrophilic handle on proteins for bioconjugation.
B Lee, S Sun, E Jiménez-Moreno, AA Neves, GJL Bernardes
Bioorganic & Medicinal Chemistry
(2018)
26
(doi: 10.1016/j.bmc.2018.02.028)
Sustainable Polysulfides for Oil Spill Remediation: Repurposing Industrial Waste for Environmental Benefit
MJH Worthington, CJ Shearer, LJ Esdaile, JA Campbell, CT Gibson, SK Legg, Y Yin, NA Lundquist, JR Gascooke, IS Albuquerque, JG Shapter, GG Andersson, DA Lewis, GJL Bernardes, JM Chalker
Advanced Sustainable Systems
(2018)
2
(doi: 10.1002/adsu.201800024)
Artificial Intelligence Recognizes β-Lapachone as an Allosteric 5- Lipoxygenase Inhibitor
G Bernardes, T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, SA Lobo, A Koeberle, F Corzana, E N. da Silva Júnior, O Werz
(2018)
(doi: 10.26434/chemrxiv.6026795.v1)
Chemo- and Regioselective Lysine Modification on Native Proteins
MJ Matos, BL Oliveira, N Martínez-Sáez, A Guerreiro, PMSD Cal, J Bertoldo, M Maneiro, E Perkins, J Howard, MJ Deery, JM Chalker, F Corzana, G Jiménez-Osés, GJL Bernardes
Journal of the American Chemical Society
(2018)
140
(doi: 10.1021/jacs.7b12874)
Antikörpergerichtete Therapien: Quo vadis?
T Rodrigues, GJL Bernardes
Angewandte Chemie
(2018)
130
(doi: 10.1002/ange.201712185)
A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism
VE Zwicker, BL Oliveira, JH Yeo, ST Fraser, GJL Bernardes, EJ New, KA Jolliffe
Angew Chem Int Ed Engl
(2018)
58
(doi: 10.1002/anie.201812489)
A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis
KR Scroggie, LJ Alcock, MJ Matos, GJL Bernardes, MV Perkins, JM Chalker
Peptide Science
(2018)
110
(doi: 10.1002/pep2.24069)
Development of Antibody-Directed Therapies: Quo Vadis?
T Rodrigues, GJL Bernardes
Angewandte Chemie (International ed. in English)
(2018)
57
(doi: 10.1002/anie.201712185)
A Thioether-directed Palladium-cleavable Linker for Targeted Bioorthogonal Drug Decaging
BJ Stenton, BL Oliveira, MJ Matos, L Sinatra, GJL Bernardes
Chemical Science
(2018)
9
(doi: 10.1039/c8sc00256h)
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer.
VJ Somovilla, IA Bermejo, IS Albuquerque, N Martínez-Sáez, J Castro-López, F García-Martín, I Compañón, H Hinou, S Nishimura, J Jiménez-Barbero, JL Asensio, A Avenoza, JH Busto,, R Hurtado-Guerrero, JM Peregrina, GJ Lopes Bernardes, F Corzana1
Journal of the American Chemical Society
(2017)
139
(doi: 10.1021/jacs.7b09447)
Chemoselective Installation of Amine Bonds on Proteins Through Aza-Michael Ligation
AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, VJ Somovilla, T Rodrigues, K Nicholls, B Xie, G Jiménez-Osés, KM Brindle, AA Neves, GJL Bernardes
J Am Chem Soc
(2017)
139
(doi: 10.1021/jacs.7b10702)
Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites
J Dadová, K-J Wu, PG Isenegger, JC Errey, GJL Bernardes, JM Chalker, L Raich, C Rovira, BG Davis
ACS Central Science
(2017)
3
(doi: 10.1021/acscentsci.7b00341)
Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez‐Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJL Bernardes
Angewandte Chemie
(2017)
129
(doi: 10.1002/ange.201708847)
Oxetane Grafts Installed Site-Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez-Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJ Lopes Bernardes
Angewandte Chemie International Edition
(2017)
56
(doi: 10.1002/anie.201708847)
Enhanced permeability and binding activity of isobutylene-grafted peptides
S Sun, I Compañón, N Martínez-Sáez, JD Seixas, O Boutureira, F Corzana, GJL Bernardes
ChemBioChem
(2017)
19
(doi: 10.1002/cbic.201700586)
Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils
GJ Lopes Bernardes
Chemistry - A European Journal
(2017)
23
(doi: 10.1002/chem.201702871)
A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases.
JB Bertoldo, T Rodrigues, L Dunsmore, FA Aprile, MC Marques, LA Rosado, O Boutureira, TB Steinbrecher, W Sherman, F Corzana, H Terenzi, GJL Bernardes
Chem
(2017)
3
(doi: 10.1016/j.chempr.2017.07.009)
Nickel-Catalyzed Azide–Alkyne Cycloaddition To Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water
WG Kim, ME Kang, JB Lee, MH Jeon, S Lee, J Lee, B Choi, PMSD Cal, S Kang, J-M Kee, GJL Bernardes, J-U Rohde, W Choe, SY Hong
Journal of the American Chemical Society
(2017)
139
(doi: 10.1021/jacs.7b06338)
Inverse electron demand Diels–Alder reactions in chemical biology
GJ Lopes Bernardes, BL Oliveira, Z Guo
Chemical Society Reviews
(2017)
46
(doi: 10.1039/c7cs00184c)
Correction: Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages
MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos
Nature communications
(2017)
8
(doi: 10.1038/ncomms15673)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal. 

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme

 

Check out Gonçalo's Google Scholar and the groups LinkedIn for more information. 

Yusuf Hamied Department of Chemistry
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