Publications

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Currently displaying 101 - 120 of 272 publications

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A Structural Ensemble of a Tau-Microtubule Complex Reveals Regulatory Tau Phosphorylation and Acetylation Mechanisms

ZF Brotzakis, PR Lindstedt, R Taylor, GJL Bernardes, M Vendruscolo

biorxiv

(2020)

2020.11.10.376285

(doi: 10.1101/2020.11.10.376285)

Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody.

J Macías-León, IA Bermejo, A Asín, A García-García, I Compañón, E Jiménez-Moreno, H Coelho, V Mangini, IS Albuquerque, F Marcelo, JL Asensio, GJL Bernardes, HJ Joshi, R Fiammengo, O Blixt, R Hurtado-Guerrero, F Corzana

Chem Commun (Camb)

(2020)

15137

(doi: 10.1039/d0cc06349e)

Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide

P Henriques, L Dello Iacono, A Gimeno, A Biolchi, MR Romano, A Arda, GJL Bernardes, J Jimenez-Barbero, F Berti, R Rappuoli, R Adamo

Proceedings of the National Academy of Sciences of the United States of America

(2020)

117

29795

(doi: 10.1073/pnas.2011385117)

meCLICK-Seq, a Substrate-Hijacking and RNA Degradation Strategy for the Study of RNA Methylation

S Mikutis, M Gu, E Sendinc, ME Hazemi, H Kiely-Collins, D Aspris, GS Vassiliou, Y Shi, K Tzelepis, GJL Bernardes

ACS Cent Sci

(2020)

2196

(doi: 10.1021/acscentsci.0c01094)

Mechanistic insights into transition metal-mediated bioorthogonal uncaging reactions

E Latocheski, GM Dal Forno, TM Ferreira, BL Oliveira, GJL Bernardes, JB Domingos

Chem Soc Rev

(2020)

7710

(doi: 10.1039/d0cs00630k)

Sequential dual site-selective protein labelling enabled by lysine modification.

MJ Matos, L Brown, B Bernardim, A Guerreiro, G Jiménez-Osés, GJL Bernardes

Bioorganic & Medicinal Chemistry

(2020)

115783

(doi: 10.1016/j.bmc.2020.115783)

Serine-Selective Bioconjugation.

JC Vantourout, SR Adusumalli, KW Knouse, DT Flood, A Ramirez, NM Padial, A Istrate, K Maziarz, JN deGruyter, RR Merchant, JX Qiao, MA Schmidt, MJ Deery, MD Eastgate, PE Dawson, GJL Bernardes, PS Baran

Journal of the American Chemical Society

(2020)

142

17236

(doi: 10.1021/jacs.0c05595)

Biomimetic peptide self-assembly for functional materials.

A Levin, TA Hakala, L Schnaider, GJL Bernardes, E Gazit, TPJ Knowles

Nature reviews. Chemistry

(2020)

615

(doi: 10.1038/s41570-020-0215-y)

Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

JD Seixas, BB Sousa, MC Marques, A Guerreiro, R Traquete, T Rodrigues, IS Albuquerque, MFQ Sousa, AR Lemos, PMF Sousa, TM Bandeiras, D Wu, SK Doyle, CV Robinson, AN Koehler, F Corzana, PM Matias, GJL Bernardes

RSC Chemical Biology

(2020)

251

(doi: 10.1039/d0cb00033g)

Selective N-Terminal Cysteine Protein Modification with Cyclopropenones

A Istrate, CD Navo, BB Sousa, MC Marques, M Deery, A Bond, F Corzana, G Jiménez-Osés, G Bernardes

(2020)

(doi: 10.26434/chemrxiv.12866873.v1)

Selective N-Terminal Cysteine Protein Modification with Cyclopropenones

A Istrate, CD Navo, BB Sousa, MC Marques, M Deery, A Bond, F Corzana, G Jiménez-Osés, G Bernardes

(2020)

(doi: 10.26434/chemrxiv.12866873)

Protein–Protein Conjugates: Tyrosine Delivers

MB Geeson, GJL Bernardes

ACS central science

(2020)

1473

(doi: 10.1021/acscentsci.0c01008)

A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening.

BB Sousa, MFQ Sousa, MC Marques, JD Seixas, JA Brito, PM Matias, GJL Bernardes, A Roldão

Bioprocess Biosyst Eng

(2020)

209

(doi: 10.1007/s00449-020-02421-6)

Tetrazine carbon nanotubes for pretargeted in vivo ‘click‐to‐release’ bioorthogonal tumour imaging

H Li, J Conde, A Guerreiro, GJL Bernardes

Angewandte Chemie

(2020)

132

16023

(doi: 10.1002/ange.202008012)

Tetrazine Carbon Nanotubes for Pretargeted In Vivo “Click‐to‐Release” Bioorthogonal Tumour Imaging

H Li, J Conde, A Guerreiro, GJL Bernardes

Angewandte Chemie International Edition

(2020)

16023

(doi: 10.1002/anie.202008012)

Rücktitelbild: Tetrazine Carbon Nanotubes for Pretargeted In Vivo “Click‐to‐Release” Bioorthogonal Tumour Imaging (Angew. Chem. 37/2020)

H Li, J Conde, A Guerreiro, GJL Bernardes

Angewandte Chemie

(2020)

132

16388

(doi: 10.1002/ange.202010067)

Back Cover: Tetrazine Carbon Nanotubes for Pretargeted In Vivo “Click‐to‐Release” Bioorthogonal Tumour Imaging (Angew. Chem. Int. Ed. 37/2020)

H Li, J Conde, A Guerreiro, GJL Bernardes

Angewandte Chemie International Edition

(2020)

16248

(doi: 10.1002/anie.202010067)

Continuous Flow Reactors from Microfluidic Compartmentalization of Enzymes within Inorganic Microparticles

TA Hakala, F Bialas, Z Toprakcioglu, B Bräuer, KN Baumann, A Levin, GJL Bernardes, CFW Becker, TPJ Knowles

ACS Applied Materials & Interfaces

(2020)

32951

(doi: 10.1021/acsami.0c09226)

Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors

K McAulay, EA Hoyt, M Thomas, M Schimpl, MS Bodnarchuk, HJ Lewis, D Barratt, D Bhavsar, DM Robinson, MJ Deery, DJ Ogg, GJL Bernardes, RA Ward, MJ Waring, JG Kettle

Journal of the American Chemical Society

(2020)

142

10358

(doi: 10.1021/jacs.9b13391)

Synthesis, characterization and photoinduced CO-release by manganese( i ) complexes

AL Amorim, A Guerreiro, VA Glitz, DF Coimbra, AJ Bortoluzzi, GF Caramori, AL Braga, A Neves, GJL Bernardes, RA Peralta

New Journal of Chemistry

(2020)

10892

(doi: 10.1039/d0nj02260h)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal.

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

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EMBO Fellowships

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Human Science Frontier Programme

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