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- Currently displaying 121 - 140 of 264 publications
Machine learning for target discovery in drug development
Current Opinion in Chemical Biology
(2019)
56
16
(doi: 10.1016/j.cbpa.2019.10.003)
A Sweet Galactose Transfer – Metabolic Oligosaccharide Engineering as a Tool to Study Glycans in Plasmodium Infection
(2019)
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification.
ACS central science
(2019)
5
1417
(doi: 10.1021/acscentsci.9b00467)
Evaluation of linker length effects on a BET bromodomain probe
Chem Commun (Camb)
(2019)
55
10128
(doi: 10.1039/c9cc05054j)
Ethynylbenziodoxolone Reactivity in Cysteine Bioconjugation
Chem
(2019)
5
1932
(doi: 10.1016/j.chempr.2019.07.014)
Overexpression of osmosensitive Ca2+-activated channel TMEM63B promotes migration in HEK293T cells
Biochemistry
(2019)
626010
(doi: 10.1101/626010)
Overexpression of Osmosensitive Ca2+-Permeable Channel TMEM63B Promotes Migration in HEK293T Cells
Biochemistry
(2019)
58
2861
(doi: 10.1021/acs.biochem.9b00224)
Tetrazine-Triggered Release of Carboxylic-Acid-Containing Molecules for Activation of an Anti-inflammatory Drug.
ChemBioChem
(2019)
20
1541
(doi: 10.1002/cbic.201900098)
Triaminopyrimidine derivatives as transmembrane HCl transporters
Organic & Biomolecular Chemistry
(2019)
17
5633
(doi: 10.1039/c9ob00725c)
Development of a self-immolative linker for tetrazine-triggered release of alcohols in cells.
Organic & biomolecular chemistry
(2019)
17
5725
(doi: 10.1039/c9ob01167f)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation.
Angew Chem Int Ed Engl
(2019)
58
6640
(doi: 10.1002/anie.201901405)
Dissecting celastrol with machine learning to unveil dark pharmacology
Chemical communications (Cambridge, England)
(2019)
55
6369
(doi: 10.1039/c9cc03116b)
Computational advances in combating colloidal aggregation in drug discovery.
Nature Chemistry
(2019)
11
402
(doi: 10.1038/s41557-019-0234-9)
Potassium Arylethynyltrifluoroborate as an Unstrained Dienophile for Ultrafast and On Demand Activation of Bioorthogonal IEDDA Reactions
(2019)
(doi: 10.26434/chemrxiv.8038685.v1)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
Angewandte Chemie
(2019)
131
6712
(doi: 10.1002/ange.201901405)
Synthesis, characterization and biological evaluation of new manganese metal carbonyl compounds that contain sulfur and selenium ligands as a promising new class of CORMs.
Dalton Trans
(2019)
48
5574
(doi: 10.1039/c9dt00616h)
Norbornene Probes for the Detection of Cysteine Sulfenic Acid in Cells
ACS chemical biology
(2019)
14
594
(doi: 10.1021/acschembio.8b01104)
Azabicyclic vinyl sulfones for residue-specific dual protein labelling Electronic supplementary information (ESI) available: Detailed methods and additional characterisation. See DOI: 10.1039/c9sc00125e
Chem Sci
(2019)
10
4515
(doi: 10.1039/c9sc00125e)
Natural product-drug conjugates for modulation of TRPV1-expressing tumors.
Bioorganic & medicinal chemistry
(2019)
27
2531
(doi: 10.1016/j.bmc.2019.03.025)
A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia
Leukemia
(2019)
33
2155
(doi: 10.1038/s41375-019-0434-8)
