Publications

Tips on using this search form

All search terms are case-insensitive
If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
To reset the search form, click here

Currently displaying 1 - 20 of 260 publications

Controlled Self-Immolative Release of β-Lapachone via an Opti- mized para-Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy

JB Becher, N Dutta, CD Navo, L Dunsmore, R Misteli, E Gil de Montes, GG Simpson, CC Alewine, G Jiménez-Osés, GJL Bernardes

Journal of the American Chemical Society

(2025)

jacs.5c17598

(doi: 10.1021/jacs.5c17598)

A Cathepsin B‐Triggered CO‐Releasing Molecule with a Non‐Toxic Metal Core for Targeted Tumor Delivery

I Černauskienė, E Izquierdo‐García, S Keller, H Betts, K Cariou, V Marchán, G Gasser, GJL Bernardes

Angewandte Chemie International Edition

(2025)

e13808

(doi: 10.1002/anie.202513808)

A Cathepsin B‐Triggered CO‐Releasing Molecule with a Non‐Toxic Metal Core for Targeted Tumor Delivery

I Černauskienė, E Izquierdo‐García, S Keller, H Betts, K Cariou, V Marchán, G Gasser, GJL Bernardes

Angewandte Chemie

(2025)

e13808

(doi: 10.1002/ange.202513808)

Advances in Proximity-Assisted Bioconjugation

M Canzano, GJL Bernardes

Accounts of chemical research

(2025)

2939

(doi: 10.1021/acs.accounts.5c00368)

Tumor-Specific STING Agonist Synthesis via a Two-Component Prodrug System

N-S Hsu, C Tang, RV Mendes, C Labão-Almeida, CV Dos Reis, AR Coelho, MC Marques, M Cabeza Cabrerizo, R Misteli, TPC Rooney, M Hyvönen, F Corzana, R Fior, GJL Bernardes

Nature Chemistry

(2025)

1941

(doi: 10.1038/s41557-025-01930-9)

[2.2.1]Heterobicyclic Bromovinyl Sulfones for Thiol-Triggered Strategies in Linker Chemistry: Aza- vs Oxa-Norbornadienic Systems.

M Carranza, AT Carmona, C Maya, E Gil de Montes, AV Vasco, GJL Bernardes, AJ Moreno-Vargas

Bioconjug Chem

(2025)

2079

(doi: 10.1021/acs.bioconjchem.5c00371)

A Charge-Driven Strategy for Covalent Modification and Modulation of Biomolecular Condensates.

Z Chen, L Liu, J Cattin, TPJ Knowles, GJL Bernardes

J Am Chem Soc

(2025)

147

28558

(doi: 10.1021/jacs.5c06625)

A De Novo Luciferase Bioconjugate for the Cas13-Based Detection of Influenza A.

M Canzano, JL Harman, Y Méndez, A Quijano-Rubio, D-A Silva, GJL Bernardes

JACS Au

(2025)

3914

(doi: 10.1021/jacsau.5c00576)

LuxSit Pro and sPro: Next-Generation Designed Luciferases for Bioluminescent Reporting and Complementation-Based Detection

R Vergara, J Wagner, P Kamalian, JL Harman, N Lara, ES Fischer, GJL Bernardes, A Quijano-Rubio, D-A Silva

(2025)

(doi: 10.1101/2025.07.21.665742)

Immunodiagnostic plasma amino acid residue biomarkers detect cancer early and predict treatment response.

C Tang, P Corredeira, S Casimiro, Q Shi, Q Han, W Sukdao, A Cavaco, C Melo-Alvim, CO Matos, C Abreu, S Walsh, G Nogueira-Costa, L Ribeiro, R Sousa, AL Barradas, JE Fonseca, L Costa, EV Yates, GJL Bernardes

Nat Commun

(2025)

6474

(doi: 10.1038/s41467-025-61685-2)

Targeted Protein Modification with an Antibody-Based System

O Rimon, J Konc, I Černauskienė, M Ali, V Roy Chowdhury, P Sormanni, GJL Bernardes, M Vendruscolo

ACS Cent Sci

(2025)

1364

(doi: 10.1021/acscentsci.5c00651)

Organic Carbon Monoxide Prodrugs Activated by Endogenous Reactive Oxygen Species for Targeted Delivery

I Cernauskiene, CD Navo, C Labão-Almeida, RS J Proctor, BH Gless, WT Khaw, C Tang, MM Muriel-Olaya, G Jiménez-Osés, GJL Bernardes

J Am Chem Soc

(2025)

147

24691

(doi: 10.1021/jacs.5c05952)

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies

M Ghirardello, A Guerreiro, C Bretón, I Compañón, J Zabalza, V Mangini, JM Peregrina, GJL Bernardes, F Corzana

Chemistry (Weinheim an der Bergstrasse, Germany)

(2025)

e202501286

(doi: 10.1002/chem.202501286)

An Expanded View of RNA Modification with Carbohydrate-Based Metabolic Probes.

ME Hazemi, MB Geeson, FM Müller, S Mikutis, AJ Enright, GJL Bernardes

Jacs Au

(2025)

2309

(doi: 10.1021/jacsau.5c00249)

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

BH Gless, E Jones, C Labão‐Almeida, C Tang, N Gottscheber, R Couto, GJL Bernardes

Angewandte Chemie

(2025)

137

e202502268

(doi: 10.1002/ange.202502268)

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups.

BH Gless, E Jones, C Labão-Almeida, C Tang, N Gottscheber, R Couto, GJL Bernardes

Angewandte Chemie International Edition

(2025)

e202502268

(doi: 10.1002/anie.202502268)

Bifunctional Phagocytic Synapse Enhancers for Cancer Immunotherapy

V Sabatino, S Fleisch, C Tang, FM Müller, C Labão-Almeida, WT Khaw, S Hogan, DR Hicks, M Fontes, AR Coelho, W Yang, I Sarkar, D Shome, AV Vidal, M Cabeza-Cabrerizo, T Rohm, RM Reijmers, D Kaymak, F Gerster, D Baker, R Fior, G Hutter, GJL Bernardes

(2025)

(doi: 10.1101/2025.03.13.642658)

Correction to "Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform".

D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman

Analytical chemistry

(2025)

4251

(doi: 10.1021/acs.analchem.5c00703)

Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform

D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman

Analytical Chemistry

(2024)

290

(doi: 10.1021/acs.analchem.4c04188)

Technologies for targeted RNA degradation and induced RNA decay

S Mikutis, GJL Bernardes

Chemical reviews

(2024)

124

13301

(doi: 10.1021/acs.chemrev.4c00472)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal.

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

Fundação para a Ciência e a Tecnologia

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme

Check out Gonçalo's Google Scholar and the groups LinkedIn for more information.