Publications

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Currently displaying 21 - 40 of 271 publications

Organic Carbon Monoxide Prodrugs Activated by Endogenous Reactive Oxygen Species for Targeted Delivery

I Cernauskiene, CD Navo, C Labão-Almeida, RS J Proctor, BH Gless, WT Khaw, C Tang, MM Muriel-Olaya, G Jiménez-Osés, GJL Bernardes

J Am Chem Soc

(2025)

147

24691

(doi: 10.1021/jacs.5c05952)

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies

M Ghirardello, A Guerreiro, C Bretón, I Compañón, J Zabalza, V Mangini, JM Peregrina, GJL Bernardes, F Corzana

Chemistry (Weinheim an der Bergstrasse, Germany)

(2025)

e202501286

(doi: 10.1002/chem.202501286)

An Expanded View of RNA Modification with Carbohydrate-Based Metabolic Probes

ME Hazemi, MB Geeson, FM Müller, S Mikutis, AJ Enright, GJL Bernardes

Jacs Au

(2025)

2309

(doi: 10.1021/jacsau.5c00249)

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups.

BH Gless, E Jones, C Labão-Almeida, C Tang, N Gottscheber, R Couto, GJL Bernardes

Angew Chem Int Ed Engl

(2025)

e202502268

(doi: 10.1002/anie.202502268)

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

BH Gless, E Jones, C Labão‐Almeida, C Tang, N Gottscheber, R Couto, GJL Bernardes

Angewandte Chemie

(2025)

137

e202502268

(doi: 10.1002/ange.202502268)

Bifunctional Phagocytic Synapse Enhancers for Cancer Immunotherapy

V Sabatino, S Fleisch, C Tang, FM Müller, C Labão-Almeida, WT Khaw, S Hogan, DR Hicks, M Fontes, AR Coelho, W Yang, I Sarkar, D Shome, AV Vidal, M Cabeza-Cabrerizo, T Rohm, RM Reijmers, D Kaymak, F Gerster, D Baker, R Fior, G Hutter, GJL Bernardes

(2025)

(doi: 10.1101/2025.03.13.642658)

Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform (vol 97, pg 290, 2025)

D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman

Analytical chemistry

(2025)

4251

(doi: 10.1021/acs.analchem.5c00703)

Ultra-sensitive protein aggregate quantification assays for neurodegenerative diseases on the Simoa platform

D Böken, Z Xia, JYL Lam, E Fertan, Y Wu, EA English, J Konc, F Layburn, GJL Bernardes, H Zetterberg, MR Cheetham, D Klenerman

Anal Chem

(2024)

290

(doi: 10.1021/acs.analchem.4c04188)

Technologies for Targeted RNA Degradation and Induced RNA Decay

S Mikutis, GJL Bernardes

Chemical reviews

(2024)

124

13301

(doi: 10.1021/acs.chemrev.4c00472)

Non-Natural MUC1 Glycopeptide Homogeneous Cancer Vaccine with Enhanced Immunogenicity and Therapeutic Activity

A Guerreiro, I Compañón, FS Lazaris, C Labão-Almeida, P Oroz, M Ghirardello, MC Marques, F Corzana, GJL Bernardes

Angewandte Chemie (International ed. in English)

(2024)

e202411009

(doi: 10.1002/anie.202411009)

Small Molecule RNA Degraders.

J Bonet-Aleta, T Maehara, BA Craig, GJL Bernardes

Angew Chem Int Ed Engl

(2024)

e202412925

(doi: 10.1002/anie.202412925)

Designed endocytosis-inducing proteins degrade targets and amplify signals.

B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, T Schlichthaerle, JZ Zhang, Y Wang, I Goreshnik, CW Chiu, A Chazin-Gray, S Chan, S Gerben, A Murray, S Wang, J O'Neill, L Yi, R Yeh, A Misquith, A Wolf, LM Tomasovic, DI Piraner, MJ Duran Gonzalez, NR Bennett, P Venkatesh, M Ahlrichs, C Dobbins, W Yang, X Wang, DD Sahtoe, D Vafeados, R Mout, S Shivaei, L Cao, L Carter, L Stewart, JB Spangler, KT Roybal, PJ Greisen, X Li, GJL Bernardes, CR Bertozzi, D Baker

Nature

(2024)

638

(doi: 10.1038/s41586-024-07948-2)

Proximity-driven site-specific cyclization of phage-displayed peptides

L Brown, AV Vidal, AL Dias, T Rodrigues, A Sigurdardottir, T Journeaux, S O'Brien, TV Murray, P Ravn, M Papworth, GJL Bernardes

Nature communications

(2024)

7308

(doi: 10.1038/s41467-024-51610-4)

Gold(III)-Induced Amide Bond Cleavage In Vivo: A Dual Release Strategy via π-Acid Mediated Allyl Substitution

VB Unnikrishnan, V Sabatino, F Amorim, MF Estrada, CD Navo, G Jimenez-Oses, R Fior, GJL Bernardes

J Am Chem Soc

(2024)

146

23240

(doi: 10.1021/jacs.4c05582)

On-Demand Thio-Succinimide Hydrolysis for the Assembly of Stable Protein-Protein Conjugates

AV Vasco, RJ Taylor, Y Méndez, GJL Bernardes

J Am Chem Soc

(2024)

146

20709

(doi: 10.1021/jacs.4c03721)

Design of a bispecific antibody to block ironendocytosis-driven metastasis

MC Marques, AR Coelho, R Rodriguez, GJL Bernardes

FEBS OPEN BIO

(2024)

285

Homogeneous multi-payload antibody-drug conjugates.

T Journeaux, GJL Bernardes

Nature Chemistry

(2024)

854

(doi: 10.1038/s41557-024-01507-y)

Targeted protein editing with an antibody-based system

M Vendruscolo, O Rimon, J Konc, M Ali, VR Chowdhury, P Sormanni, G Bernardes

(2024)

(doi: 10.21203/rs.3.rs-3947849/v1)

Cathepsin B Processing Is Required for the In Vivo Efficacy of Albumin–Drug Conjugates

B Bernardim, J Conde, T Hakala, JB Becher, M Canzano, AV Vasco, TPJ Knowles, J Cameron, GJL Bernardes

Bioconjugate Chemistry

(2024)

132

(doi: 10.1021/acs.bioconjchem.3c00478)

Design and Evaluation of PROTACs Targeting Acyl Protein Thioesterase 1

G Lopes Bernardes

Chembiochem

(2024)

e202300736

(doi: 10.1002/cbic.202300736)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

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