Publications

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Currently displaying 181 - 200 of 252 publications

Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents.

B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes

Nature Communications

(2016)

13128

(doi: 10.1038/ncomms13128)

Bioorthogonal Strategy for Bioprocessing of Specific-Site-Functionalized Enveloped Influenza-Virus-Like Particles.

SB Carvalho, JM Freire, MG Moleirinho, F Monteiro, D Gaspar, MARB Castanho, MJT Carrondo, PM Alves, GJL Bernardes, C Peixoto

Bioconjugate chemistry

(2016)

2386

(doi: 10.1021/acs.bioconjchem.6b00372)

Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, W-L Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, M-L Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis

Science (New York, N.Y.)

(2016)

354

aag1465

(doi: 10.1126/science.aag1465)

Unveiling (−)-Englerin A as a Modulator of L-Type Calcium Channels

T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes

Angewandte Chemie

(2016)

128

11243

(doi: 10.1002/ange.201604336)

Tn Antigen Mimics Based on sp2-Iminosugars with Affinity for an anti-MUC1 Antibody

EMS Fernández, CD Navo, N Martínez-Sáez, R Gonçalves-Pereira, VJ Somovilla, A Avenoza, JH Busto, GJL Bernardes, G Jiménez-Osés, F Corzana, JMG Fernández, CO Mellet, JM Peregrina

Organic Letters

(2016)

3890

(doi: 10.1021/acs.orglett.6b01899)

Correction: Iminoboronates are efficient intermediates for selective, rapid and reversible N -terminal cysteine functionalisation

H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois

Chemical science

(2016)

6280

(doi: 10.1039/c6sc90045c)

Unveiling (-)-EnglerinA as a Modulator of L-Type Calcium Channels

T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes

Angewandte Chemie International Edition

(2016)

11077

(doi: 10.1002/anie.201604336)

Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation

H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois

Chemical science

(2016)

5052

(doi: 10.1039/c6sc01520d)

Construction of homogeneous antibody-drug conjugates using site-selective protein chemistry

P Akkapeddi, S-A Azizi, AM Freedy, PMSD Cal, PMP Gois, GJL Bernardes

Chemical science

(2016)

2954

(doi: 10.1039/c6sc00170j)

Urban Endocrine Disruptors Targeting Breast Cancer Proteins

D Montes-Grajales, GJL Bernardes, J Olivero-Verbel

Chem Res Toxicol

(2016)

150

(doi: 10.1021/acs.chemrestox.5b00342)

Enhancing Methotrexate Tolerance with Folate Tagged Liposomes in Arthritic Mice

E Nogueira, F Lager, D Le Roux, P Nogueira, J Freitas, C Charvet, G Renault, A Loureiro, CR Almeida, A Ohradanova-Repic, C Machacek, GJL Bernardes, A Moreira, H Stockinger, M Burnet, AM Carmo, AC Gomes, A Preto, G Bismuth, A Cavaco-Paulo

Journal of biomedical nanotechnology

(2015)

2243

(doi: 10.1166/jbn.2015.2170)

Site-selective protein-modification chemistry for basic biology and drug development

N Krall, FP da Cruz, O Boutureira, GJL Bernardes

Nature Chemistry

(2015)

102

(doi: 10.1038/NCHEM.2393)

Sulfur-Limonene Polysulfide: A Material Synthesized Entirely from Industrial By-Products and Its Use in Removing Toxic Metals from Water and Soil.

MP Crockett, AM Evans, MJH Worthington, IS Albuquerque, AD Slattery, CT Gibson, JA Campbell, DA Lewis, GJL Bernardes, JM Chalker

Angewandte Chemie (International ed. in English)

(2015)

1714

(doi: 10.1002/anie.201508708)

An N‐Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species

JD Seixas, M Chaves-Ferreira, D Montes-Grajales, AM Gonçalves, AR Marques, LM Saraiva, J Olivero-Verbel, CC Romão, GJL Bernardes

Chemistry – A European Journal

(2015)

14708

(doi: 10.1002/chem.201502474)

Peptide Anchor for Folate-Targeted Liposomal Delivery.

E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJL Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JPFC Rossi, AC Gomes, A Preto, A Cavaco-Paulo

Biomacromolecules

(2015)

2904

(doi: 10.1021/acs.biomac.5b00823)

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana

Angewandte Chemie International Edition

(2015)

9830

(doi: 10.1002/anie.201502813)

Size controlled protein nanoemulsions for active targeting of folate receptor positive cells

A Loureiro, E Nogueira, NG Azoia, MP Sárria, AS Abreu, U Shimanovich, A Rollett, J Härmark, H Hebert, G Guebitz, GJL Bernardes, A Preto, AC Gomes, A Cavaco-Paulo

Colloids and surfaces. B, Biointerfaces

(2015)

135

(doi: 10.1016/j.colsurfb.2015.06.073)

Deciphering the Non‐Equivalence of Serine and Threonine O‐Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti‐MUC1 Antibody

N Martínez-Sáez, J Castro-López, J Valero-González, D Madariaga, I Compañón, VJ Somovilla, M Salvadó, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana

Angewandte Chemie - International Edition

(2015)

9830

(doi: 10.1002/anie.201502813)

Synthesis of fluorosugar reagents for the construction of well-defined fluoroglycoproteins

M Salvadó, B Amgarten, S Castillón, GJL Bernardes, O Boutureira

Organic Letters

(2015)

2836

(doi: 10.1021/acs.orglett.5b01259)

Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation

E Lira-Navarrete, M de Las Rivas, I Compañón, MC Pallarés, Y Kong, J Iglesias-Fernández, GJL Bernardes, JM Peregrina, C Rovira, P Bernadó, P Bruscolini, H Clausen, A Lostao, F Corzana, R Hurtado-Guerrero

Nature communications

(2015)

6937

(doi: 10.1038/ncomms7937)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal.

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

Fundação para a Ciência e a Tecnologia

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme