Publications

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Currently displaying 181 - 200 of 268 publications

Nickel-Catalyzed Azide–Alkyne Cycloaddition To Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water

WG Kim, ME Kang, JB Lee, MH Jeon, S Lee, J Lee, B Choi, PMSD Cal, S Kang, J-M Kee, GJL Bernardes, J-U Rohde, W Choe, SY Hong

J Am Chem Soc

(2017)

139

12121

(doi: 10.1021/jacs.7b06338)

Inverse electron demand Diels-Alder reactions in chemical biology

GJ Lopes Bernardes, BL Oliveira, Z Guo

Chem Soc Rev

(2017)

4895

(doi: 10.1039/c7cs00184c)

Corrigendum: A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages

MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos

Nat Commun

(2017)

15673

(doi: 10.1038/ncomms15673)

Frontispiece: Site‐Selective Modification of Proteins with Oxetanes

O Boutureira, N Martínez‐Sáez, KM Brindle, AA Neves, F Corzana, GJL Bernardes

Chemistry – A European Journal

(2017)

chem.201782762

(doi: 10.1002/chem.201782762)

Protein modification

TT-L Kwan, O Boutureira, EC Frye, SJ Walsh, MK Gupta, S Wallace, Y Wu, F Zhang, HF Sore, WRJD Galloway, JW Chin, M Welch, GJL Bernardes, DR Spring

Chem Sci

(2017)

3871

(doi: 10.1039/c6sc05313k)

Site-Selective Modification of Proteins with Oxetanes

O Boutureira, N Martínez-Sáez, KM Brindle, AA Neves, F Corzana, GJ Lopes Bernardes

Chemistry

(2017)

6483

(doi: 10.1002/chem.201700745)

A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages

MMA Pereira, I Mahú, E Seixas, N Martinéz-Sánchez, N Kubasova, RM Pirzgalska, P Cohen, MO Dietrich, M López, GJL Bernardes, AI Domingos

Nat Commun

(2017)

14967

(doi: 10.1038/ncomms14967)

Site-selective installation of BASHY fluorescent dyes to Annexin V for targeted detection of apoptotic cells.

PMSD Cal, F Sieglitz, FMF Santos, C Parente Carvalho, A Guerreiro, JB Bertoldo, U Pischel, PMP Gois, GJL Bernardes

Chemical Communications

(2017)

368

(doi: 10.1039/c6cc08671c)

Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

E Jiménez‐Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez‐Osés, GJL Bernardes

Angewandte Chemie

(2017)

129

249

(doi: 10.1002/ange.201609607)

Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells.

E Jiménez-Moreno, Z Guo, BL Oliveira, IS Albuquerque, A Kitowski, A Guerreiro, O Boutureira, T Rodrigues, G Jiménez-Osés, GJL Bernardes

Angewandte Chemie (International ed. in English)

(2017)

243

(doi: 10.1002/anie.201609607)

Norbornene probes for the study of cysteine oxidation

LJ Alcock, KD Farrell, MT Akol, GH Jones, MM Tierney, HB Kramer, TL Pukala, GJL Bernardes, MV Perkins, JM Chalker

Tetrahedron

(2017)

1220

(doi: 10.1016/j.tet.2017.11.011)

Oxidative Activation of C-S Bonds with an Electropositive Nitrogen Promoter Enables Orthogonal Glycosylation of Alkyl over Phenyl Thioglycosides.

A Kitowski, E Jiménez-Moreno, M Salvadó, J Mestre, S Castillón, G Jiménez-Osés, O Boutureira, GJL Bernardes

Organic Letters

(2017)

5490

(doi: 10.1021/acs.orglett.7b02886)

In situ characterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR

R Li, R Rajan, WCV Wong, DG Reid, MJ Duer, VJ Somovilla, N Martinez-Saez, GJL Bernardes, R Hayward, CM Shanahan

Chemical communications (Cambridge, England)

(2017)

13316

(doi: 10.1039/c7cc06624d)

Trends in therapeutic drug conjugates for bacterial diseases: a patent review

PMSD Cal, MJ Matos, GJL Bernardes

Expert Opin Ther Pat

(2016)

179

(doi: 10.1080/13543776.2017.1259411)

Antibody-drug conjugates: The missing link.

T Rodrigues, GJL Bernardes

Nature chemistry

(2016)

1088

(doi: 10.1038/nchem.2685)

A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells

BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez‐Osés, GJL Bernardes

Angewandte Chemie

(2016)

128

14903

(doi: 10.1002/ange.201608438)

A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells

BL Oliveira, Z Guo, O Boutureira, A Guerreiro, G Jiménez-Osés, GJL Bernardes

Angewandte Chemie (International ed. in English)

(2016)

14683

(doi: 10.1002/anie.201608438)

Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents.

T Rodrigues, F Sieglitz, GJL Bernardes

Chem Soc Rev

(2016)

6130

(doi: 10.1039/c5cs00916b)

Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, R Raj, S Faulkner, MRJ Vallée, A Phanumartwiwath, OD Coleman, ML Thézénas, M Khan, SRG Galan, L Lercher, MW Schombs, S Gerstberger, ME Palm-Espling, AJ Baldwin, BM Kessler, TDW Claridge, S Mohammed, BG Davis

Science (New York, N.Y.)

(2016)

354

Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents.

B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, IS Albuquerque, E Perkins, F Corzana, ACB Burtoloso, G Jiménez-Osés, GJL Bernardes

Nature Communications

(2016)

13128

(doi: 10.1038/ncomms13128)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

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