Publications

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Currently displaying 241 - 260 of 268 publications

Chemical site-selective protein modification: Development of a traceless vascular targeting ADC for cancer therapy

GJL Bernardes, D Neri, BG Davis

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2012)

243

Building well-defined glycoproteins

GJL Bernardes, BG Davis

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2012)

243

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

AC Pena, N Penacho, L Mancio-Silva, R Neres, JD Seixas, AC Fernandes, CC Romão, MM Mota, GJL Bernardes, A Pamplona

Antimicrob Agents Chemother

(2012)

1281

(doi: 10.1128/aac.05571-11)

Developing drug molecules for therapy with carbon monoxide.

CC Romão, WA Blättler, JD Seixas, GJL Bernardes

Chemical Society reviews

(2012)

3571

(doi: 10.1039/c2cs15317c)

Selenenylsulfide‐Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human “Hepatic Se Metabolite A”

O Boutureira, GJL Bernardes, M Fernández-González, DC Anthony, BG Davis

Angewandte Chemie (International ed. in English)

(2011)

1432

(doi: 10.1002/anie.201106658)

A Traceless Vascular‐Targeting Antibody–Drug Conjugate for Cancer Therapy

GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, J Scheuermann, D Neri

Angewandte Chemie International Edition

(2011)

941

(doi: 10.1002/anie.201106527)

Direct radiolabelling of proteins at cysteine using [ 18 F]-fluorosugars

O Boutureira, GJL Bernardes, F D'Hooge, BG Davis

Chemical communications (Cambridge, England)

(2011)

10010

(doi: 10.1039/c1cc13524d)

Methods for converting cysteine to dehydroalanine on peptides and proteins

JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis

Chemical Science

(2011)

1666

(doi: 10.1039/c1sc00185j)

Towards Improved Therapeutic CORMs: Understanding the Reactivity of CORM-3 with Proteins

T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão

Curr Med Chem

(2011)

3361

(doi: 10.2174/092986711796504583)

Site‐Selective Traceless Staudinger Ligation for Glycoprotein Synthesis Reveals Scope and Limitations

GJL Bernardes, L Linderoth, KJ Doores, O Boutureira, BG Davis

Chembiochem : a European journal of chemical biology

(2011)

1383

(doi: 10.1002/cbic.201100125)

A "tag-and-modify" approach to site-selective protein modification.

JM Chalker, GJL Bernardes, BG Davis

Accounts of Chemical Research

(2011)

730

(doi: 10.1021/ar200056q)

Chemical Site-selective Modification of Proteins: Tools for Synthetic Biology

GJL Bernardes

FASEB JOURNAL

(2011)

A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates

EJ Grayson, GJL Bernardes, JM Chalker, O Boutureira, JR Koeppe, BG Davis

Angew Chem Int Ed Engl

(2011)

4127

(doi: 10.1002/anie.201006327)

CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl-Lysozyme Complex

T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão

Journal of the American Chemical Society

(2011)

133

1192

(doi: 10.1021/ja108820s)

Site-selective chemoenzymatic construction of synthetic glycoproteins using endoglycosidases

M Fernández-González, O Boutureira, GJL Bernardes, JM Chalker, MA Young, JC Errey, BG Davis

Chemical Science

(2010)

709

(doi: 10.1039/c0sc00265h)

Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting

GJL Bernardes, R Kikkeri, M Maglinao, P Laurino, M Collot, SY Hong, B Lepenies, PH Seeberger

Org Biomol Chem

(2010)

4987

(doi: 10.1039/c0ob00372g)

Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins

O Boutureira, F D'Hooge, M Fernández-González, GJL Bernardes, M Sánchez-Navarro, JR Koeppe, BG Davis

Chemical communications (Cambridge, England)

(2010)

8142

(doi: 10.1039/c0cc01576h)

Chemical Protein Modification

GJL Bernardes, JM Chalker, BG Davis

(2010)

(doi: 10.1002/9783527630516.ch3)

Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology

JM Chalker, GJL Bernardes, YA Lin, BG Davis

Chemistry an Asian Journal

(2009)

630

(doi: 10.1002/asia.200800427)

Combined Approaches to the Synthesis and Study of Glycoproteins

GJL Bernardes, B Castagner, PH Seeberger

ACS Chem Biol

(2009)

703

(doi: 10.1021/cb900014n)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal.

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme

Check out Gonçalo's Google Scholar and the groups LinkedIn for more information.