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  • Currently displaying 221 - 240 of 252 publications
Author(s)
Publication title
Journal Name
Publication year
Spacer length shapes drug release and therapeutic efficacy of traceless disulfide-linked ADCs targeting the tumor neovasculature
M Steiner, I Hartmann, E Perrino, G Casi, S Brighton, I Jelesarov, GJL Bernardes, D Neri
Chemical Science
(2013)
4
Generation of carbon monoxide releasing molecules (CO-RMs) as drug candidates for the treatment of acute liver injury: Targeting of CO-RMs to the liver
AR Marques, L Kromer, DJ Gallo, N Penacho, SS Rodrigues, JD Seixas, GJL Bernardes, PM Reis, SL Otterbein, RA Ruggieri, ASG Gonçalves, AML Gonçalves, MND Matos, I Bento, LE Otterbein, WA Blättler, CC Romão
Organometallics
(2012)
31
Fucose -specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format
K Zuberbühler, G Casi, GJL Bernardes, D Neri
Chem Commun (Camb)
(2012)
48
A novel carbon monoxide-releasing molecule fully protects mice from severe malaria.
AC Pena, N Penacho, L Mancio-Silva, R Neres, JD Seixas, AC Fernandes, CC Romão, MM Mota, GJL Bernardes, A Pamplona
Antimicrobial agents and chemotherapy
(2012)
56
Developing drug molecules for therapy with carbon monoxide
CC Romão, WA Blättler, JD Seixas, GJL Bernardes
Chemical Society Reviews
(2012)
41
Building well-defined glycoproteins
GJL Bernardes, BG Davis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
243
Chemical site-selective protein modification: Development of a traceless vascular targeting ADC for cancer therapy
GJL Bernardes, D Neri, BG Davis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
243
Chemical site-selective radiolabelling of proteins using fluorosugars
O Boutureira, GJL Bernardes, BG Davis
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2012)
243
Selenenylsulfide‐Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human “Hepatic Se Metabolite A”
O Boutureira, GJL Bernardes, M Fernández-González, DC Anthony, BG Davis
Angewandte Chemie (International ed. in English)
(2011)
51
A traceless vascular-targeting antibody-drug conjugate for cancer therapy.
GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, J Scheuermann, D Neri
Angewandte Chemie International Edition
(2011)
51
Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars
O Boutureira, GJL Bernardes, F D'Hooge, BG Davis
Chemical communications (Cambridge, England)
(2011)
47
Methods for converting cysteine to dehydroalanine on peptides and proteins
JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis
Chemical Science
(2011)
2
Towards improved therapeutic CORMs: understanding the reactivity of CORM-3 with proteins.
T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão
Curr Med Chem
(2011)
18
Site-selective traceless Staudinger ligation for glycoprotein synthesis reveals scope and limitations.
GJL Bernardes, L Linderoth, KJ Doores, O Boutureira, BG Davis
Chembiochem
(2011)
12
A "tag-and-modify" approach to site-selective protein modification.
JM Chalker, GJL Bernardes, BG Davis
Accounts of chemical research
(2011)
44
A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates
EJ Grayson, GJL Bernardes, JM Chalker, O Boutureira, JR Koeppe, BG Davis
Angewandte Chemie International Edition
(2011)
50
CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl−Lysozyme Complex
T Santos-Silva, A Mukhopadhyay, JD Seixas, GJL Bernardes, CC Romão, MJ Romão
Journal of the American Chemical Society
(2011)
133
Chemical Site-selective Modification of Proteins: Tools for Synthetic Biology
GJL Bernardes
FASEB JOURNAL
(2011)
25
Site-selective chemoenzymatic construction of synthetic glycoproteins using endoglycosidases
M Fernández-González, O Boutureira, GJL Bernardes, JM Chalker, MA Young, JC Errey, BG Davis
Chemical Science
(2010)
1
Design, synthesis and biological evaluation of carbohydrate -functionalized cyclodextrins and liposomes for hepatocyte -specific targeting
GJL Bernardes, R Kikkeri, M Maglinao, P Laurino, M Collot, SY Hong, B Lepenies, PH Seeberger
Organic & biomolecular chemistry
(2010)
8

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

Fundação para a Ciência e a Tecnologia

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme