Publications

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Currently displaying 221 - 240 of 261 publications

Curative properties of noninternalizing antibody-drug conjugates based on maytansinoids

E Perrino, M Steiner, N Krall, GJL Bernardes, F Pretto, G Casi, D Neri

Cancer Res

(2014)

2569

(doi: 10.1158/0008-5472.CAN-13-2990)

A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors

N Krall, F Pretto, W Decurtins, GJL Bernardes, CT Supuran, D Neri

Angewandte Chemie International Edition

(2014)

4231

(doi: 10.1002/anie.201310709)

Rationally designed short polyisoprenol-linked PglB substrates for engineered polypeptide and protein N-glycosylation

F Liu, B Vijayakrishnan, A Faridmoayer, TA Taylor, TB Parsons, GJL Bernardes, M Kowarik, BG Davis

Journal of the American Chemical Society

(2014)

136

566

(doi: 10.1021/ja409409h)

Protein micro- and nano-capsules for biomedical applications

U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco-Paulo

Chem Soc Rev

(2013)

1361

(doi: 10.1039/c3cs60376h)

Highlights from the 48th EUCHEM conference on stereochemistry, Burgenstock, Switzerland, May 2013

GJL Bernardes

Chem Commun (Camb)

(2013)

8578

(doi: 10.1039/c3cc90259e)

Site-specific chemical modification of antibody fragments using traceless cleavable linkers.

GJL Bernardes, M Steiner, I Hartmann, D Neri, G Casi

Nature Protocols

(2013)

2079

(doi: 10.1038/nprot.2013.121)

Synthetically defined glycoprotein vaccines: Current status and future directions

R Adamo, A Nilo, B Castagner, O Boutureira, F Berti, GJL Bernardes

Chemical Science

(2013)

2995

(doi: 10.1039/c3sc50862e)

Spacer length shapes drug release and therapeutic efficacy of traceless disulfide-linked ADCs targeting the tumor neovasculature

M Steiner, I Hartmann, E Perrino, G Casi, S Brighton, I Jelesarov, GJL Bernardes, D Neri

Chem. Sci.

(2013)

297

(doi: 10.1039/C2SC21107F)

Chemoselective transformations for bioimaging and targeted therapeutics

GJL Bernardes

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

(2013)

S55

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

AR Marques, L Kromer, DJ Gallo, N Penacho, SS Rodrigues, JD Seixas, GJL Bernardes, PM Reis, SL Otterbein, RA Ruggieri, ASG Gonçalves, AML Gonçalves, MN De Matos, I Bento, LE Otterbein, WA Blättler, CC Romão

Organometallics

(2012)

5810

(doi: 10.1021/om300360c)

Fucose -specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format

K Zuberbühler, G Casi, GJL Bernardes, D Neri

Chem Commun (Camb)

(2012)

7100

(doi: 10.1039/c2cc32412a)

A novel carbon monoxide-releasing molecule fully protects mice from severe malaria.

AC Pena, N Penacho, L Mancio-Silva, R Neres, JD Seixas, AC Fernandes, CC Romão, MM Mota, GJL Bernardes, A Pamplona

Antimicrob Agents Chemother

(2012)

1281

(doi: 10.1128/aac.05571-11)

Developing drug molecules for therapy with carbon monoxide.

CC Romão, WA Blättler, JD Seixas, GJL Bernardes

Chem Soc Rev

(2012)

3571

(doi: 10.1039/c2cs15317c)

Chemical site-selective protein modification: Development of a traceless vascular targeting ADC for cancer therapy

GJL Bernardes, D Neri, BG Davis

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2012)

243

Chemical site-selective radiolabelling of proteins using fluorosugars

O Boutureira, GJL Bernardes, BG Davis

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2012)

243

Building well-defined glycoproteins

GJL Bernardes, BG Davis

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2012)

243

Selenenylsulfide-Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human "Hepatic Se Metabolite A"

O Boutureira, GJL Bernardes, M Fernández-González, DC Anthony, BG Davis

Angew Chem Int Ed Engl

(2011)

1432

(doi: 10.1002/anie.201106658)

A traceless vascular-targeting antibody-drug conjugate for cancer therapy.

GJL Bernardes, G Casi, S Trüssel, I Hartmann, K Schwager, J Scheuermann, D Neri

Angewandte Chemie International Edition

(2011)

941

(doi: 10.1002/anie.201106527)

Direct radiolabelling of proteins at cysteine using [18F]- fluorosugars

O Boutureira, GJL Bernardes, F D'Hooge, BG Davis

Chemical Communications

(2011)

10010

(doi: 10.1039/c1cc13524d)

Methods for converting cysteine to dehydroalanine on peptides and proteins

JM Chalker, SB Gunnoo, O Boutureira, SC Gerstberger, M Fernández-González, GJL Bernardes, L Griffin, H Hailu, CJ Schofield, BG Davis

Chemical Science

(2011)

1666

(doi: 10.1039/c1sc00185j)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal.

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme

Check out Gonçalo's Google Scholar and the groups LinkedIn for more information.