Publications

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Currently displaying 201 - 220 of 266 publications

Tn Antigen Mimics Based on sp 2‑Iminosugars with Affinity for an anti-MUC1 Antibody

EMS Fernández, CD Navo, N Martínez-Sáez, R Gonçalves-Pereira, VJ Somovilla, A Avenoza, JH Busto, GJL Bernardes, G Jiménez-Osés, F Corzana, JMG Fernández, CO Mellet, JM Peregrina

Organic Letters

(2016)

3890

(doi: 10.1021/acs.orglett.6b01899)

Correction: Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation.

H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois

Chemical Science

(2016)

6280

(doi: 10.1039/c6sc90045c)

Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.

T Rodrigues, F Sieglitz, VJ Somovilla, PMSD Cal, A Galione, F Corzana, GJL Bernardes

Angew Chem Int Ed Engl

(2016)

11077

(doi: 10.1002/anie.201604336)

Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation

H Faustino, MJSA Silva, LF Veiros, GJL Bernardes, PMP Gois

Chemical Science

(2016)

5052

(doi: 10.1039/c6sc01520d)

Construction of homogeneous antibody-drug conjugates using site-selective protein chemistry

P Akkapeddi, S-A Azizi, AM Freedy, PMSD Cal, PMP Gois, GJL Bernardes

Chem Sci

(2016)

2954

(doi: 10.1039/c6sc00170j)

Urban Endocrine Disruptors Targeting Breast Cancer Proteins.

D Montes-Grajales, GJL Bernardes, J Olivero-Verbel

Chem Res Toxicol

(2016)

150

(doi: 10.1021/acs.chemrestox.5b00342)

Enhancing methotrexate tolerance with folate tagged liposomes in arthritic mice

E Nogueira, F Lager, D Le Roux, P Nogueira, J Freitas, C Charvet, G Renault, A Loureiro, CR Almeida, A Ohradanova-Repic, C Machacek, GJL Bernardes, A Moreira, H Stockinger, M Burnet, AM Carmo, AC Gomes, A Preto, G Bismuth, A Cavaco-Paulo

Journal of biomedical nanotechnology

(2015)

2243

(doi: 10.1166/jbn.2015.2170)

Site-selective protein-modification chemistry for basic biology and drug development.

N Krall, FP da Cruz, O Boutureira, GJL Bernardes

Nature chemistry

(2015)

102

(doi: 10.1038/NCHEM.2393)

Sulfur-Limonene Polysulfide: A Material Synthesized Entirely from Industrial By-Products and Its Use in Removing Toxic Metals from Water and Soil.

MP Crockett, AM Evans, MJH Worthington, IS Albuquerque, AD Slattery, CT Gibson, JA Campbell, DA Lewis, GJL Bernardes, JM Chalker

Angewandte Chemie - International Edition

(2015)

1714

(doi: 10.1002/anie.201508708)

An N-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species

JD Seixas, M Chaves-Ferreira, D Montes-Grajales, AM Gonçalves, AR Marques, LM Saraiva, J Olivero-Verbel, CC Romão, GJL Bernardes

Chemistry (Weinheim an der Bergstrasse, Germany)

(2015)

14708

(doi: 10.1002/chem.201502474)

Peptide Anchor for Folate-Targeted Liposomal Delivery

E Nogueira, IC Mangialavori, A Loureiro, NG Azoia, MP Sárria, P Nogueira, J Freitas, J Härmark, U Shimanovich, A Rollett, G Lacroix, GJL Bernardes, G Guebitz, H Hebert, A Moreira, AM Carmo, JPFC Rossi, AC Gomes, A Preto, A Cavaco-Paulo

Biomacromolecules

(2015)

2904

(doi: 10.1021/acs.biomac.5b00823)

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody

N Martínez-Sáez, J Castro-Lõpez, J Valero-González, D Madariaga, I Compañõn, VJ Somovilla, M Salvadõ, JL Asensio, J Jiménez-Barbero, A Avenoza, JH Busto, GJL Bernardes, JM Peregrina, R Hurtado-Guerrero, F Corzana

Angewandte Chemie International Edition

(2015)

9830

(doi: 10.1002/anie.201502813)

Size controlled protein nanoemulsions for active targeting of folate receptor positive cells

A Loureiro, E Nogueira, NG Azoia, MP Sárria, AS Abreu, U Shimanovich, A Rollett, J Härmark, H Hebert, G Guebitz, GJL Bernardes, A Preto, AC Gomes, A Cavaco-Paulo

Colloids and Surfaces B: Biointerfaces

(2015)

135

(doi: 10.1016/j.colsurfb.2015.06.073)

Synthesis of fluorosugar reagents for the construction of well-defined fluoroglycoproteins.

M Salvadó, B Amgarten, S Castillón, GJL Bernardes, O Boutureira

Organic letters

(2015)

2836

(doi: 10.1021/acs.orglett.5b01259)

Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation

E Lira-Navarrete, M de Las Rivas, I Compañón, MC Pallarés, Y Kong, J Iglesias-Fernández, GJL Bernardes, JM Peregrina, C Rovira, P Bernadó, P Bruscolini, H Clausen, A Lostao, F Corzana, R Hurtado-Guerrero

Nat Commun

(2015)

6937

(doi: 10.1038/ncomms7937)

Folic acid-tagged protein nanoemulsions loaded with CORM-2 enhance the survival of mice bearing subcutaneous A20 lymphoma tumors.

A Loureiro, GJL Bernardes, U Shimanovich, MP Sárria, E Nogueira, A Preto, AC Gomes, A Cavaco-Paulo

Nanomedicine: Nanotechnology, Biology and Medicine

(2015)

1077

(doi: 10.1016/j.nano.2015.02.022)

Advances in chemical protein modification

O Boutureira, GJL Bernardes

Chemical reviews

(2015)

115

2174

(doi: 10.1021/cr500399p)

A contribution to the rational design of Ru(CO)₃Cl₂L complexes for in vivo delivery of CO

JD Seixas, MFA Santos, A Mukhopadhyay, AC Coelho, PM Reis, LF Veiros, AR Marques, N Penacho, AML Gonçalves, MJ Romão, GJL Bernardes, T Santos-Silva, CC Romão

Dalton Trans

(2015)

5058

(doi: 10.1039/c4dt02966f)

Collagen labelling with an azide-proline chemical reporter in live cells.

B Amgarten, R Rajan, N Martínez-Sáez, BL Oliveira, IS Albuquerque, RA Brooks, DG Reid, MJ Duer, GJL Bernardes

Chem Commun (Camb)

(2015)

5250

(doi: 10.1039/c4cc07974d)

An artificial CO-releasing metalloprotein built by histidine-selective metallation.

IS Albuquerque, HF Jeremias, M Chaves-Ferreira, D Matak-Vinkovic, O Boutureira, CC Romão, GJL Bernardes

Chem Commun (Camb)

(2015)

3993

(doi: 10.1039/c4cc10204e)

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal.

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme

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