The Bernardes Group

Dr Koki Nakatsu

Publications

Chemical Protein Synthesis via Direction-Switching One-Pot Peptide Ligation Enabled by Orthogonal Cysteinyl Protection
K Nakatsu, F Yoshitomi, H Onoda, R Shikimachi, K Arita, A Okamoto, H Murakami, G Hayashi
Journal of the American Chemical Society
(2026)
148
(doi: 10.1021/jacs.5c20510)
Chemical protein synthesis via one-pot multiple peptide ligation strategies
G Hayashi, K Nakatsu, S Suzuki, Y Nakajima
(2024)
(doi: 10.1039/bk9781839169328-00001)
One-pot ligation of multiple peptide segments via N-terminal thiazolidine deprotection chemistry.
G Nakamura, K Nakatsu, G Hayashi
(2024)
698
(doi: 10.1016/bs.mie.2024.04.020)
Repetitive Thiazolidine Deprotection Using a Thioester-Compatible Aldehyde Scavenger for One-Pot Multiple Peptide Ligation
K Nakatsu, A Okamoto, G Hayashi, H Murakami
Angewandte Chemie International Edition
(2022)
61
(doi: 10.1002/anie.202206240)
Fmoc-Compatible and C-terminal-Sequence-Independent Peptide Alkyl Thioester Formation Using Cysteinylprolyl Imide
K Nakatsu, M Yanase, G Hayashi, A Okamoto
Org Lett
(2020)
22
(doi: 10.1021/acs.orglett.0c01450)
Toolbox for chemically synthesized histone proteins.
K Nakatsu, G Hayashi, A Okamoto
Current opinion in chemical biology
(2020)
58
(doi: 10.1016/j.cbpa.2020.04.016)
Cysteinylprolyl imide (CPI) peptide: a highly reactive and easily accessible crypto-thioester for chemical protein synthesis
M Yanase, K Nakatsu, CJ Cardos, Y Konda, G Hayashi, A Okamoto
Chemical science
(2019)
10
(doi: 10.1039/c9sc00646j)

Postdoctoral researcher

Email address

kn448@cam.ac.uk

Interested in joining the GBernardesLab?

We are always looking for enthusiastic and bright researchers to join the lab. If you are interested in joining the group, please contact Gonçalo directly at gb453@cam.ac.uk.

All applications should include a cover letter that highlights your research interests, a full CV, and the names and addresses of two referees.

Funded PhD and Postdoctoral positions will be advertised when available through the university jobs portal. 

Postdoctoral researchers are encouraged to obtain their own fellowships. Potential funding sources include:

Marie Curie Actions

Royal Society Newton International Fellowships

EMBO Fellowships

Swiss National Foundation

Human Science Frontier Programme

 

Check out Gonçalo's Google Scholar and the groups LinkedIn for more information. 

Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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